Refractory to IT Morphine
- Pain history
- 9 years severe chronic pain
- Pain in lower back and lower extremities
- IT pump implanted 6 months ago
- Pain etiology and treatment history
- Severe traumatic injury to lower lumbar area
- Failed multiple therapies, including lumbar sympathetic blocks and spinal cord stimulator trial
- Takes NSAIDs, antidepressants, oral opioids, and IT morphine
- Patient is getting limited pain relief and has become intolerant of IT morphine treatment as doses were escalated
- PRIALT introduced
- PRIALT could be offered as a non-opioid alternative to IT morphine*
*The combination of PRIALT with IT opiates has not
been studied in placebo-controlled clinical trials and
is not recommended.6
Important Safety Information
Reduced Level of Consciousness
In clinical trials, 2% of PRIALT-treated patients became unresponsive or stuporous. If reduced levels of consciousness occur, discontinue PRIALT until the event resolves, and other etiologies (e.g., meningitis) must be considered.
Elevation of Serum Creatine Kinase
In clinical trials, serum creatine kinase (CK) levels above the upper limit of normal (ULN) were reported in 40% of patients, with 11% of patients having CK levels >3 times ULN. Incidences were higher during the first 2 months of treatment. Serum CK should be monitored periodically. If these symptoms continue and CK levels remain elevated or continue to rise, reduce the dose or discontinue the use of PRIALT.
Please see full Prescribing Information, including BOXED Warning, and click here for additional Important Safety Information.